I have not seen the WIP Nate is doing, But agree. If one had the set up and skill to jig and program the CNC you could do as many as you want. and one would be exactly the same as the next.
This brings up another question. Is the finished knife made by this method considered a custom knife or semi custom, or a mid tech etc. Its gets muddy and probably a question better left for another post.
As to the initial question. Yes its possible to do alot with one of these mills. In the right hands there is nothing you cant make with a vertical mill.