I started a thread like this one awhile ago and I'm sure that there where many before that and they all seem to end. In the same place: no one really knows / has done a scientific test on edge wear on end grain company epicurean but the 2 are probably close enough that the decision comes down to other factors like application, cleanup, feel, appearance and personal taste.
Like most nuts on here I have end grain. Maple, poly, and epi.
However, I recently got a screaming deal on a massive epi "big block" series board... It's 26"x18"x1" thick. My reason for getting it was that my endorsing board had previously been living on the counter and by the sink and taking a lot of abuse /water /missuse. Being as near indestructible as any knife friendly surface can be, the epi made a much better "always out" board. It takes hot pans, but water, oil, blood, sticky goo, vinegar, food coloring, red wine... and it just shrugs it off and asks for more.
For long cutathons I still bring out the end grain. I enjoy cutting on the natural wood more... It just feels nice. Wood also seems to have much better dampening properties (absorbs/deadens shock).
However, I have to say that while the epi looks and feels harder, it still cuts and scores and I haven't noticed a difference in edge retention since I started using it more.