Generally speaking, one should pay one's debts, however they are incurred. I recall that while gambling debts were not legally collectible, the trick was not to let someone lose more than they could realistically be expected to pay. Then, after a long night, you would take the loser to breakfast, on the way to his bank. Non-payment was not an option.
Even in the real world, if you don't pay your debts, bad things can happen; i.e., no one will give you stuff on credit anymore, or you lose your house. But that is all easily foreseeable. People who borrow lots of money at exorbitant rates are essentially gamblers. Most gamblers don't have a lot of sense, but they have high hopes.