Stainless clad obviously improves corrosion resistance over the majority of the blade. It doesn’t patina, which could be good or bad, depending on your preferences. It isn't as easy to grind when thinning but this is not a biggie (it's low carbon, so quite soft). It definitely limits your polishing options but it generally gives s pretty nice contrast between the core and cladding, especially once the core steel patina or if you use a stone that generates contrast. Forcing a patina of the core steel with an acid etch will highlight the lamination line dramatically.
Ironclad knives patina fairly quickly. Once patinated, they are somewhat less reactive. There are a few ironclads that are known to be quite reactive (some Mazakis and early Tanaka blue2 damascus come to mind) but the significant majority will just patina rapidly in use as long as you don't leave them wet for ages.
As
@HumbleHomeCook said, no effect at all on the cutting edge.
FWIW, maybe 2/3 of my carbon knives are ironclad. In my case, this is because I don't really mind either way. My main interests are the metallurgy of steels/heat treatments and how the knives perform in food, so I just buy knives according to grinds or smiths and sharpeners that I want to try.
If I was an avid polisher, I'd have more ironclad knives.
I don't treat my ironclad knives any differently to my stainless clad or fully stainless knives: I do a quick rinse off under running water, then a quick dry on a tea towel after cutting acidic ingredients (onion, lemon , tomato) or if I'm not going to be using the knife in the next few minutes. A full wash and dry at the end of prep (with a little air drying before putting the knife away, just to be sure).